Angiology 2000, 51:S65S68. (They noted that this age range corresponds to more than 80% of the consumers of the drug and to about 99% of all malignant cancers). View the data on our Hypothyroidism Research page. Most of the time, doctors tell patients treated with LT4 that any side effects will be temporary and almost ineluctable, and are usually dealt with through dose reduction. This website is for information purposes only. Furthermore, the geometric expansion of hypothyroidism cases in the past decade only thinly conceals an agenda to promote the synthetic form of T4 known as levothyroxine sodium (trade name Synthroid), since with each new disease case the patient is converted into a lifelong customer. Maybe because they "treat" only with T4 and not T3? The estimated 2.3 million new cases indicate that 1 in every 8 cancers diagnosed in . I have so much to say about this I could write a book. This article is copyrighted by GreenMedInfo LLC, 2013, Some features are currently member only features. Non-small cell lung cancer is the most common type of lung cancer, accounting for about 81% of all cases. Nah, I would give this much credence. PLoSone 2011, 11:e27547. You must log in or register to reply here. When a high-risk patient presents with one or more lung nodules, the path ahead and next steps seems obvious. Thank you for posting it, I agree we all need as much knowledge as we can get! I am convinced that my lung cancer is related to the thyroid/auto immune issues I've had for years. May be of interest: Study: Millions Treated for Hypothyroidism At Risk for, Non-small cell lung cancer - Adenocarcinoma, Non-small cell lung cancer - Squamous cell, Top 5 Questions to Ask Your Lung Cancer Doctor, Patient & Caregiver Network Member Resources, Not A Member Yet? Factors found to be associated with mortality were age, senile dementia, congestive heart failure, chronic renal failure, and a history of cerebrovascular disease. Oops, I just saw that I posted the same article. The study looked at the prevalence of breast, colorectal, gastric and lung cancer in 18 Italian Regions during 2010 and correlated this data with sales of LT4 in 2009, focusing on women aged 30-84. PMID: 23539727, [16] Alan R Gaby. [14] In other words, you can normalize the main clinically measurable parameter associated with low thyroid function, i.e. The first blood test typically done to diagnose hypothyroidism measures the level of thyroid-stimulating hormone (TSH) in the blood. Baked or Fried avocado fries [Vegetarian]. However, I do not believe it was out of the blue now. Whether it should be treated remains controversial. Medical Authoritys System Kills: FDA-Approved Dru Cognitive Impairment, Memory Loss and Alzheimer's Soy Lecithin: How It Negatively Affects Your Healt Cannabis Oil Cures Cancer -Lincoln Horsley's Story New Information Dissolves Illusions About Vaccines Grounding Helps Thin Dangerously Thick Blood and F Tart Cherries Relieve Osteoarthritis Pain, Lieberman's Massive Connections To Big Pharma, Utopian 'Harvest Your Own' Groceries Coming Up. [3], An old clinical observation on the relationship between lung cancer and thyroid function reported that patients were characterized by a low concentration of T3 and an increased T4/T3 ratio due to a decrease of 5-monodeiodination (DI). Importance: Whether radioactive iodine (RAI) therapy for hyperthyroidism can increase cancer risk remains a controversial issue in medicine and public health. In fact, a 2004 study in subjects with normal thyroid function found that administration of tyrosine leads to a significant reduction in serum TSH and improvement in mood in winter compared with placebo, while the combined synthetic T4-T3 supplement leads to a worsening of mood in summer and no improvement in winter, indicating supporting glandular function is superior to 'replacement' therapy, as well as the role seasonality may play in hormone function and hormone treatment interventions. [12] Cesarone MR, Belcaro G, Nicolaides AN, Incandela L, De Sanctis MT, Barsotti A: San Valentino epidemiologic project. Increased sleepiness. I have been reading Izabella Wentz. You are using an out of date browser. Levothyroxine therapy and serum free thyroxine and free triiodothyronine concentrations. The Goji Berry: The Jolly Super Food That Gives Yo How to Prevent and Treat Insect Bites Without Hars Supreme Court Rules Drug Companies Exempt From Law Spain Study Confirms Hemp Oil Cures Cancer without Wheatgrass Turns Gray Hair Back to Its Natural Color, Medicinal Cannabis Used To Prevent Cancer Growth. 'A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low . [1] Hercbergs AH, Ashur-Fabian O, Garfield D: Thyroid hormone and cancer: clinical studies of hypothyroidism in oncology. (31) 3351-3382 | 3351-3272 | 3351-3141 | 3351-3371. location of blind frog ranch associe-se. undefined will no longer be visible to you including posts, replies, and photos. Correlation is not causation. Overtreatment, of course, is the hallmark danger of overdiagnosis. hyperthyroidism. A distorted idea of human nature is sold when people are treated as "the market. Acta Endocrinol 1988, 118:460464. hyperthyroidism. If people do not wish to find out all they can about their disease that is fine too. Article published in Wakeup-World.Com. video where the doc is talking about the study , i wlll link study and video below. Obesity epidemic caused by EMF exposures in the ho War on Health - The FDA's Cult of Tyranny. J Exp Biol 2010, 213:28992911. Join the Patient & Caregiver Network. Study: Millions Treated for Hypothyroidism At Risk of Lung Cancer. [4] Ratcliffe JG, Stack BH, Burt RW, Radcliffe WA, Spilg WG, Cuthbert J, Kennedy RS: Thyroid function in lung cancer. and our Data sources: The Medline and Cochrane Library electronic databases . Overtreatment, of course, is the hallmark danger of overdiagnosis. weight loss, anorexia). " I'm not saying that there Is no link between Synthroid and lung cancer. Millions of people who were not only wrongly diagnosed with 'cancers' and subsequently aggressively treated for them with chemotherapy, radiation and surgery, are now being told that they would have been better left undiagnosed and untreated. SayerJiis founder ofGreenmedinfo.com, a reviewer at theInternational Journal of Human Nutrition and Functional Medicine,Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of theNational Health Federation, SteeringCommittee Memberof the Global Non-GMO Foundation. I bet in the previous discussion, if there was one, we would have concluded it was likely that it was because people are generally not put on enough levothyroxine. The authors also cite animal experimental research which has shown that T4 increases the oxidative stress[6] and spontaneous pulmonary metastases in mice. People read a study and think that someone like, perhaps me, is saying "it Causes lung cancer. The great open sky of imagination: for those who u Fermented Foods: Top 8 Reasons to Eat Them. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional. 2013 May ;98(5):1982-90. A study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' En 3 minutos recibirs en tu email COMPLETAMENTE GRATIS todo lo que necesitas para aumentar las ventas de tu empresa. Just go on one of the thyroid sites and read the stories. Furthermore, the geometric expansion of hypothyroidism cases in the past decade only thinly conceals an agenda to promote the synthetic form of T4 known as levothyroxine sodium (trade name Synthroid), since with each new 'disease' case the patient is converted into a lifelong customer. I honestly do not know. The reality is that most cases of hypothyroidism today are diagnosed in populations who are experiencing a combination of basic nutritional deficiencies and chemical exposures, or who are simply going through a temporary down-cycle in thyroid function following a natural change, such as the natural postpartum drop that occurs in women after giving birth. However, the study looked at the incrase of ALL lung cancers, not SCLC, so that data does not correlate with this study. Dr Childs guesses that patients on levothyroxine monotherapy may be more prone to cancer because they might be under-treated. Respiratory system Hypothyroidism weakens the respiratory muscles and decreases lung function. Study: Millions Treated for Hypothyroidism At Risk of Lung Cancer. [2], The observation that patients with small cell carcinoma of the lung often present symptoms suggestive of hyperthyroidism (i.e. The reality is that most cases of hypothyroidism today are diagnosed in populations who are experiencing a combination of basic nutritional deficiencies and chemical exposures, or who are simply going through a temporary down-cycle in thyroid function following a natural change, such as the natural postpartum drop that occurs in women after giving birth. Given the clear role that selenium deficiency plays in preventing the conversion of T4 to the far more biologically active form of thyroid hormone known as triiodothyronine (T3), which can cause an elevation of thyroxine-stimulating hormone (TSH), why call a mineral deficiency-induced decrease in T4 a monolithic disease entity such as hypothyroidism? I read somewhere about the work done many years ago which was mistakenly read and accepted 28 y/o F Low levels across the board for TSH, T3, and T4, Acid reflux drug linked to more than doubled risk of stomach cancer study, thyroiduk.org - further-reading - thyroid-diagnosis-and-treatment. [2] Meng R, Tang HY, Westfall J, London D, Cao JH, Mousa SA, Luidens M, Hercbergs A, Davis FB, Davis PJ, et al: Crosstalk between integrin v3 and estrogen receptor- is involved in thyroid hormone-induced proliferation in human lung carcinoma cells. It does not seem to quantify the increased risk, and it keeps saying it is hyperthyroidism that causes the oxidised stress. (February 2002). A total of 425 inpatients with malignant tumors were treated with ICIs at PUMCH during the study period. Find how some diseases can be healed with alternative medicine, and share your experience with Brit Med J 1978, 1:210212. Or, simply look at what the young-adult, T-score based definition of osteoporosis and osteopenia has done to convert millions of healthy middle-age and older women into drug-treatable patients, or, what the lipid hypothesis of cardiovascular disease causation has done to create a 30-billion dollar a year market in statin drugs, to fully appreciate the harms of overdiagnosis and overtreatment. [9] [10] [11] Although we should never forget that LT4 is a life-saving thyroid hormone replacement, and that one should not exclude that the pathological reason that leads to the prescription of LT4 could favor the lung cancer development also. [learn more: Is Drug-Based Medicine a Form of Human Sacrifice?] [13] Hollowell JG, Staehling NW, Flanders WD, et al. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer Posted on: Monday, August 12th 2013 at 7:15 am Written By: Sayer Ji, Founder A new study has. That's all. is the fiec part of the evangelical alliance; townhomes in avalon park; 8 ft windmill parts; why is my cash and sweep vehicle negative; nordstrom rack return policy worn shoes The authors expanded on their findings further: However, the impression we get from our experience in epidemiological studies monitoring[12] is that this drug should be prescribed more cautiously. Compression of the trachea, which may be positional, can occur with nodular goiters and thyroid cancer, and the latter can metastasize to the lungs. With the recent announcement by a National Cancer Institute commissioned expert panel that a variety of so-called 'indolent' neoplasms such as ductal carcinoma in situ (DCIS) and high-grade prostatic intraepithelial neoplasia (HGPIN), formerly understood to be forms of breast and prostate cancers, respectively, should be renamed to reflect their intrinsic benignity, a veritable sea change is occurring within the conventional medical establishment. Endocrinology 1985, 117:12011208. Even acute bouts of stress and subclinical adrenal insufficiency can cause cyclical downshifts in thyroid function. For more information, please see our If You Don't Want Older Bones, Don't Be Low In Vit Background Mortality Rate for Vaccines, or Pseudo Everything You Ever Wanted to Know About Black Seeds. Patients with incomplete information (n = 127), preexisting hypothyroidism or levothyroxine replacement before initiation of ICI therapy (n = 11), or other factors known to contribute to thyroid dysfunction after immunotherapy (n = 17) were excluded (Fig. Increased sensitivity to cold. Marketed as superior to traditional glandular forms extracted from pigs (whose endocrine glands are far more bioidentical than any other animal we know of) due to the dose-to-dose standardization of the so-called active ingredient T4 versus the natural variations in hormone concentrations found in the real thing, which incidentally contains a wide range of additional hormones including T1, T2, T3, all of which are vitally important. My Endocrinologist was, and continues to be, open about the elevated risk for thyroid cancer due to the multiple. "Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)", International Journal of Human Nutrition and Functional Medicine, Osteoporosis Is Scurvy of the Bone, Not Calcium Deficiency, 6 Bodily Tissues That Can Be Regenerated Through Nutrition, 7 Simple Ways to Unclog Your Arteries Naturally, Herbal Cream Clears 87.7% of HPV Cases Naturally, How WHOLE Turmeric Heals the Damaged Brain. To investigate the magnitude of the possible association between levothyroxine use and cancer risk, this retrospective c Endocrinology 2008, 149:22412250. [8] van Doorn J, Roelfsema F, van der Heide D: Concentration of thyroxine and 3,5,3-triiodotyronine in several rat tissue in vivo: the effect of hypothyroidism. elevated TSH, without actually improving the overall physiological situation, nor the patient's subjective experience of well being. The omnipresent environmental contaminant perchlorate, an ingredient in jet fuel, is also a primary cause of hypothyroidism, but is almost never tested for by the conventional endocrinologists in their patient evaluations. bear in the big blue house characters; colne times obituaries this week Menu Toggle. http://www.greenmedinfo.com/blog/study-millions-treated-hypothyroidism-risk-l Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer, Iodine Supplementation Support by VWT Team. A place for patients and relatives. Just for entertainment value take a look at some more dodgy correlations : I rather liked the correlation between consumption of orange marmalade and birth rate - in the years after the second world war if I remember correctly. There is also the very real possibility that T4 will not only not properly interact with thyroxine cellular receptors, but will block out what remaining natural levothyroxine the thyroid is still producing (and whose conformational state is far more health-promoting), essentially acting as an endocrine disrupter at the very moment that it is acting as intended as a TSH suppressor. This T4 blocking/endocrine-disrupting property of the synthetic form would also activate a negative feedback loop within the endocrine system, further suppressing remaining thyroid function, and resulting in the atrophy of the compromised thyroid, a iatrogenic self-fulfilling prophecy if you will. Forgot account? All the more reason to prescribe T3, I say! This T4 blocking/endocrine-disrupting property of the synthetic form would also activate a negative feedback loop within the endocrine system, further suppressing remaining thyroid function, and resulting in the atrophy of the compromised thyroid, a iatrogenic 'self-fulfilling prophecy' if you will. I wish I could say that my story was atypical. The authors delved deeper into the reason why oxidative stress taking place during T4 treatment is particularly linked to lung cancer only: The hypothesis could be that in lungs the increase of hypoxia-induced factor (HIF-1) which is determined by T4 can make oxygen much more available, increasing locally the oxidative stress together with a dangerous angiogenesis stimulation. [3], An old clinical observation on the relationship between lung cancer and thyroid function reported that patients were characterized by a low concentration of T3 and an increased T4/T3 ratio due to a decrease of 5'-monodeiodination (DI). ', Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer. [13] Hollowell JG, Staehling NW, Flanders WD. Epub 2013 Mar 28. Compared to patients without hypothyroidism, those with a high TSH level before hospitalization stayed in the hospital 1.2 days longer and had a 49% higher risk of 30-day readmission and a 43% . J Endocrinol Invest. [11] Wan J, Chai H, Yu Z, Ge W, Kang N, Xia W, Che Y: H1F-1 on angiogenic potential in human small cell carcinoma. florence nightingale concept 2 via de boleto Subclinical hypothyroidism is defined by an elevated serum thyroid-stimulating hormone (TSH) level along with a normal free thyroxine (T4) level. [12] Cesarone MR, Belcaro G, Nicolaides AN, Incandela L, De Sanctis MT, Barsotti A: San Valentino epidemiologic project. Share your experience, learn from others. One of the main drawbacks of administering T4 in isolation is the possibility that it will not convert adequately to T3, and will therefore back up causing excessive T4 activity, i.e. Those with the greatest risk of developing thyroid disorders are women who have a family history of the disease. But what can be done for patients who are at low Sin un requerimiento, el cumplimiento voluntario por parte de tu Proveedor de servicios de Internet, o los registros adicionales de un tercero, la informacin almacenada o recuperada slo para este propsito no se puede utilizar para identificarte. In the United States, autoimmune thyroid disease (Hashimoto thyroiditis) is the most common cause of hypothyroidism, but globally lack of iodine in the diet is the most common cause. Other research indicating that increased thyroid activity (hyperthyroidism) contributes to lung cancer pathogenesis was presented, including: The authors also cite animal experimental research which has shown that T4 increases the oxidative stress[6] and spontaneous pulmonary metastases in mice. Researchers are currently studying. There are many links attached. A couple of caveats to note in this study: The authors found a statistical correlation between the increase in sales of the thyroid medicine Synthroid, and an increase in lung cancer in Italy. Hashimoto's disease progresses slowly over the years. 1). Biomedicine today is awash in controversy associated with the overdiagnosis and overtreatment of asymptomatic populations. They then correlated drug sales with cancers, eliminating the contribution of age and smoking for lung cancer risk. According to data from the National Health and Nutrition Examination Survey, years 1988-1994, [13] while 0.3% of the American population exhibits overt symptoms of hypothyroidism, 14 times more (4.3%) have so-called subclinical hypothyroidism only detected via blood work. I have so many women friends and family members who have recently been diagnosed with hypothyroidism and their doctors put them all on Synthyroid. Salt, Sugar, Fat: 15 Shocking Facts From the Book Dear Doctor, Do You Really Know What Vaccines Cont Colloidal Gold: Discover the Benefits and Wonders, Scientists Explain Why HPV Vaccines Are Unsafe. Oops I have just bought my first jar of marmalade in over ten years! [4], More recently DI activity in lung cancer was found to be lower than in peripheral lung tissue.[5]. A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.'. Objectives: To examine site-specific cancer incidence and mortality and to evaluate the radiation dose-response association after RAI treatment for hyperthyroidism. 2 Hypothyroidism is the most common type of thyroid disorder, and women's risk of hypothyroidism is five to eight times higher than that of . Comp Biochem Physiol C Toxicol Pharmacol 2002, 133:475481. Physician/Author on Facebook. So I will leave it as a simple thank you for passing this along. I am going to go for a walk with my dog :)). Comp Biochem Physiol C Toxicol Pharmacol 2002, 133:475481. This is a horrible disease that ravages the body. But what can be done for patients who are at low She wrote about a product called Thyrtophin PMG. Curr Opin Endocrinol Diabetes Obes 2010, 17:432436. It's usually based on the results of blood tests. It was the therapist that I went to that referred me to a specialist who ran the correct tests. (They noted that this age range corresponds to more than 80% of the consumers of the drug and to about 99% of all malignant cancers). The authors expanded on their findings further: "However, the impression we get from our experience in epidemiological studies monitoring[12] is that this drug should be prescribed more cautiously. If it's high, the test is done again, along with a blood test for the thyroid hormone T-4. [5]Wawrzynska L, Sakowicz A, Rudzinski P, Langfort R, Kurzyna M: The conversion to triiodothyronine in the lung: comparison of activity of type I iodotironine 5 deiodinase in lung cancer with peripheral lung tissues. Thyroid dysfunction after immune checkpoint inhibitor treatment in a single-center Chinese cohort: a retrospective study Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. PLoSone 2011, 11:e27547. Thanks, I am not suggesting I believe in all that I see. I think part of sharing information here on Inspire is the discussions about the articles we share. Sub-laboratory hypothyroidism and the empirical use of Armour thyroid.Altern Med Rev. There are several books out there written about the topic. If I can help someone, fine. "A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' Tokushima J Exp Med 1991, 38:2535. Angiology 2000, 51:S65S68. The relationship between levothyroxine use and cancer risk is largely underdetermined. In discussing their findings, the authors noted that they could not exclude the possibility that the condition of hypothyroidism could favor the development of lung cancer. I have sent the link that I read today. Brit Med J 1978, 1:210212. [9] [10] [11] Although we should never forget that LT4 is a life-saving thyroid hormone replacement, and that one should not exclude that the pathological reason that leads to the prescription of LT4 could favor the lung cancer development also. This is a news report of the research, so I can't learn the details of how the science was conducted. [7] They also elaborate on a mechanism of T4-induced lung tissue toxicity: [I]n rats lung the deiodination of LT4 is the lowest compared to all the other tissues. They then correlated drug sales with cancers, eliminating the contribution of age and smoking for lung cancer risk. [14] K A Woeber. This relatively symptom-free reservoir of hypothyroid cases provides a veritable gold mine of potential office visits, billable services and drug prescriptions. Sayer Ji is the founder ofGreenmedinfo.com, a reviewer at theInternational Journal of Human Nutrition and Functional Medicine,Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of theNational Health Federation, and SteeringCommittee Memberof the Global Non-GMO Foundation. radioactive treatments. An Italian study published in the journalReproductive Biology and Endocrinology,titled Levothyroxine and lung cancer in females: the importance of oxidative stress, has raised a concerning possibility: levothyroxine (T4), one of the worlds most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). Given the clear role that selenium deficiency plays in preventing the conversion of T4 to the far more biologically active form of thyroid hormone known as triiodothyronine (T3), which can cause an elevation of thyroxine-stimulating hormone (TSH), why call a mineral deficiency-induced decrease in T4 a monolithic disease entity such as "hypothyroidism"? Intuition and Trust: a Personal Journey Through Ancient Pathways, Meditation, Yoga, Grounding & Mindfulness, Levothyroxine and lung cancer in females: the importance of oxidative stress, 2013 announcement by a National Cancer Institute, T-score based definition of osteoporosis and osteopenia, 30-billion dollar a year market in statin drugs, Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). Non-ASPS articles which could be relevant. "Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)". Or, if fluoride, mercury, or any number of xenobiotic chemicals in the environment requiring selenium-dependent glutathione-mediated detoxification is causing the low thyroid, why call chemical poisoning hypothyroidism?
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